|
|
Welcome to the Biosurfaces and Biomechanics website. Our multidisciplinary
research ranges from fundamental investigations of cell adhesion
and protein mechanics to engineering new platforms for controlling
cell behavior and understanding human disease. Central to this
research is a fundamental understanding of intersurface and intermolecular
forces and the different ways that they control interactions in
biology and bioengineering.
|
|
|
 |
 |
|
|
Molecular
Mechanics |
 |
|
Mechanical forces are critical to numerous biological
processes such as cell migration, cell adhesion, and the maintenance
of cell shape and function. Proteins both exert and resist mechanical
forces in the cell, altering cell signaling and biological function.
In cell adhesion, cell surface molecules anchor cells and transmit
mechanical forces across the membranes.
... |
|
| |
|
|
|
|
 |
|
|
Cell
Adhesion |
|
|
New tools in microfabrication are rapidly creating
new opportunities for biological research and bioengineering. We are
using these micropatterning tools to develop novel platforms for rapidly
screening compounds that alter cell function and/or stimulate stem
cell differentiation... More |
|
| |
 |
|
|
Biomaterials
and Microdevices |
|
|
|
|
|
|
|
My lab uses surface analytical approaches together
with surface engineering to understand the biology-material interface.
Our work is establishing engineering design rules for controlling
how materials interact with the biological environment, by controlling
the surface chemistry and architecture of the material surfaces. |
|
|
|
|
|
|
|
|
|
|
|
|
|
