Publications
Zhao, Y.; Knee, J.L.; Baranger, A.M. "Characterization of Two Adenosine Analogs as Fluorescence Probes in RNA" Bioorg. Chem., accepted for publication.
Anunciado, D.; Agumeh, M.; Kormos, B.L.; Beveridge, D.L.; Knee, J.L.; Baranger, A.M. "Characterization of the Dynamics of an Essential Helix in the U1A Protein by Time-Resolved Fluorescence Measurements", J. Phys. Chem. B., 2008, 112, 6122-6130
Benitex, Y.; Baranger, A.M. "Recognition of Essential Purines by the U1A Protein", BMC Biochemistry, 2007, 8:22
Yan, Z.; Ramisetty, S.R.; Bolton, P.H.; Baranger, A.M. "Selective
Recognition of RNA Helices Containing Dangling Ends by a Quinoline Derivative" ChemBioChem, 2007, 8, 1658.
Yan, Z.; Sikri, S.: Beveridge, D.L.; Baranger, A.M. "Identification of an Aminoacridine Derivative that Binds to RNA Tetraloops" J. Med. Chem., 2007, 50, 4096-4104.
Kormos, B.L.; Benitex, Y.; Baranger, A.M.; Beveridge, D.L. "Affinity and Specificity of Protein U1A-RNA Complex Formation Based on an Additive Component Free Energy Model" J. Mol. Biol., 2007, Vol. 371. Issue 5, 1405-1419.
Kormos, B.L; Baranger, A.M.; Beveridge, D.L. "A Study of Collective Atomic Fluctuations and Cooperativity in a U1A-RNA Complex Based on Molecular Dynamics Simulations" J. Struct. Biol., 2007, 157, 500.
Beveridge, D.L.; Dixit, S.B.; Kormos, B.L.; Baranger, A.M.; Jayaram, B.. "Molecular Dynamics Simulations and Free Energy Calculations on Protein-Nucleic Acid Complexes." In Computational Studies of DNA and RNA.Eds., J. Sponer and F. Lankas. Springer: New York. 2006.
Kormos, B.L; Baranger, A.M.; Beveridge, D.L. "Do
Collective Atomic fluctuations Account for Cooperative Effects? Molecular Dynamics
Studies of the U1A-RNA Complex", J. Am. Chem. Soc. 2006 ,
128 , 8992.
Zhao, Y.; Kormos, B.L.; Beveridge, D.L.; Baranger, A.M. "Molecular
Dynamics Simulation Studies of a Protein-RNA Complex with a Selectively Modified
Binding Interface" Biopolymers , 2006 , 81
, 256.
Yan, Z.; Baranger, A.M. "Binding
of an Aminoacridine Derivative to a Tetraloop RNA" Bioorganic and Medicinal
Chemistry Letters , 2004 , 14 , 5889.
Zhao, Y.; Baranger, A.M. "Design
of an Adenosine Analog that Selectively Improves the Affinity of a Mutant U1A
Protein for RNA", J. Am. Chem. Soc. , 2003 ,
125 , 2480.
Tuite, J.B.; Shiels, J.C.; Baranger, A.M. "Substitution
of an Essential Adenine in the U1A-RNA Complex with a Non-polar Isostere",
Nucleic Acids Res. , 2002 , 30 , 5269,
cover article.
Gayle, A.Y.; Baranger, A.M. "Inhibition
of the U1A-RNA Complex by an Aminoacridine Derivative", Bioorg. Med. Chem.
Lett. , 2002 , 12 , 2839-2842.
Pitici, F.; Baranger, A.M., Beveridge, D.L. "Molecular
Dynamics Simulation Studies of Induced Fit and Conformational Capture in U1A-RNA
Binding: Do Molecular Substates Code for Specificity?", Biopolymers ,
2002 , 65 , 424.
Shiels, J.C.; Tuite, J.B.; Nolan, S.J.; Baranger, A.M. "Investigation
of a Conserved Stacking Interaction in Target Site Recognition by the U1A Protein",
Nucleic Acids Res. , 2002 , 30 , 550-558.
Shiels, J.C.; Jerkovic, B.; Baranger, A.M.; Bolton, P.H. "RNA-DNA
Hybrids Containing Damaged DNA are Substrates for RNase H", Bioorg. Med.
Chem. Lett. , 2001 , 11 , 2623.
Blakaj, D.M.; McConnell, K.J.; Beveridge, D.L.; Baranger, A.M. "Molecular
Dynamics and Thermodynamics of a Protein-RNA Complex: Mutation of a Conserved
Aromatic Residue Modifies Stacking Interactions and Structural Adaptation in
the U1A-stem Loop 2 RNA Complex" J. Am. Chem. Soc. , 2001
, 123 , 2548.
Luchansky, S.; Nolan, S.J.; Baranger, A.M. "Contribution
of RNA Conformation to the Stability of a High-Affinity RNA-Protein Complex",
J. Am. Chem. Soc. 2000 , 122 , 7130.
Nolan, S.J.; Shiels, J.C.; Tuite, J.B.; Cecere, K.L.; Baranger, A.M. "Recognition
of an Essential Adenine at a Protein-RNA Interface: Comparison of the Contributions
of Hydrogen Bonds and a Stacking Interaction", J. Am. Chem. Soc. ,
1999 , 121 , 8951.