Home Research People Alumni Database of published mutants List of eJournals from the UIUC library site Links

This page has not been updated since 1999. Updates will be made in the near future.

 You can use the 'find' function of your browser to search for a residue (e.g. D132). This list, created and maintained by Ashtamurthy Pawate, is not exhaustive. If you have information on mutants and papers that  have been missed, please email pawate@uiuc.edu and they will be included.

Papers published on mutants of cytochrome bo3 and cytochrome aa3 (including reviews)
Mutations Protein Subunit Organism Authors Journal
E286Q Cytochrome bo3 I E. coli Puustinen A, Morgan JE, Verkhovsky M, Thomas JW, Gennis RB, Wikstrom M Biochemistry 31(), 10363-10369 (1992)
H333L, H334L Cytochrome bo3 I E. coli Lemon DD, Calhoun MW, Gennis RB, Woodruff WH Biochemistry 32(?), 11953-11956 (1993)
D135E,N, D188N, E286Q,A, D256N, D407N Cytochrome bo3 I E. coli Thomas JW, Puustinen A, Alben JO, Gennis RB, Wikstrom M Biochemistry 32(40), 10923-10928 (1993)
T352A,N,S, M353A, P358A, T359A,S, K362L,M,Q Cytochrome bo3 I E. coli Thomas JW, Lemieux LJ, Alben JO, Gennis RB Biochemistry 32(41), 11173-11180 (1993)
H333N,L,M,R,C,Q, H334N,L,M,R,C,Q Cytochrome bo3 I E. coli Calhoun MW, Hill JJ, Lemieux LJ, Ingledew WJ, Alben JO, Gennis RB Biochemistry 32(43), 11524-11529 (1993)
H419G,L,N,C,Y,D,M,Q, Q195E, N227D, N277H,Y, Y472H, H411G,L Cytochrome bo3 I E. coli Calhoun MW, Lemieux LJ, Thomas JW, Hill JJ, Goswitz VC, Alben JO, Gennis RB Biochemistry 32(48), 13254-13261 (1993)
P285G, E286A, Y288A,C,P,H,S, P293A Cytochrome bo3 I E. coli Thomas JW, Calhoun MW, Lemieux LJ, Puustinen A, Wikstrom M, Alben HO, Gennis RB Biochemistry 33(44), 13013-13021 (1994)
N124H, N124D, N124Q, P128A,D, G132A,R, D135N,K,E, P139A,E, N142V,D,Q, A133D, R134P, A137D, F138R,G, F140R, R134P/F140R, N124d/d135N, P128D/D135N, I131D/D135N, V136D/D135N, A137D/D135N, F138D/D135N, P139E/D135N, P139E/D135A, L141D/D135N, N142D/D135N Cytochrome bo3 I E. coli Garcia-Horsman JA, Puustinen A, Gennis RB, Wikstrom M Biochemistry 34(13), 4428-4433 (1995)
T352A,N,S, M353A, P358A, T359A,S, K362L,M,Q Cytochrome bo3 I E. coli Svensson M, Hallen S, Thomas JW, Lemieux LJ, Gennis RB, Nilsson T Biochemistry 34(15), 5252-5258 (1995)
W280F, P285G, E286A, Y288F Cytochrome bo3 I E. coli Svensson-Ek M, Thomas JW, Gennis RB, Nilsson T, Brzezinski P Biochemistry 35(42):13673-13680 (1996)
E286A Cytochrome bo3 I E. coli Watmough NJ, Katsonouri A, Little RH, Osborne JP, Furlong-Nickels E, Gennis RB, Brittain T, Greenwood C Biochemistry 36(), 13736-13742 (1997)
W136A Cytochrome bo3 I E. coli Ma J, Puustinen A, Wikstrom M, Gennis RB Biochemistry 37(34):11806-11811 (1998)
M248I, S258N, F281S, H284P, I129T, N198T, Q233H Cytochrome bo3 I E. coli Sato-Watanabe M, Mogi T, Sakamoto K, Miyoshi H, Anraku Y Biochemistry 37(37), 12744-12752 (1998)
H333L Cytochrome bo3 I E. coli Brown S, Rumbley JN, Moody Aj, Thomas JW, Gennis RB, Rich PR Biochim Biophys Acta 1183(3), 521-532 (1994)
M110I,A Cytochrome bo3 I E. coli Calhoun MW, Lemieux LJ, Garcia-Horsman JA, Thomas JW, Alben JO, Gennis RB FEBS Lett 368(3), 523-525 (1995)
E286Q,D Cytochrome bo3 I E. coli Tsubaki M, Hori H, Mogi T FEBS Lett. 416(3), 247-250 (1997)
K55Q, K362Q, R80Q, R481Q, R484Q, R257Q, E286Q, E540Q, D135N, D407N, D188N, D256N, Y173F, Y288F, E286D Cytochrome bo3 I E. coli Kawasaki M, Mogi T, Anraku Y J. Biochem. 122, 422-429 (1997)
H106G,L, M110I, N277D,Y, H284G,L,C,N,Q,W,Y, E286A,Q, Y288A,F,S, H333C,L,M,N,Q,R, H334C,L,M,N,Q,R, T352A,S, P358A, T359A,S, K362A,M,Q, H411G,L, H419N,C,D,G,L,M,Q,Y, H421G,L Cytochrome bo3 I E. coli Hosler JP, Ferguson-Miller S, Calhoun MW, Thomas JW, Hill J, Lemieux L, Ma J, Georgiou C, Fetter J, Shapleigh J, Tecklenburg MMJ, Babcock GT, Gennis RB J. Bioener Biomem 25(2), 121-136 (1993) (REVIEW)
H54A, H106A,Q,M, H284A,Q,M, H333A, H334A, H411A, H419A, H421A,Q,M Cytochrome bo3 I E. coli Minagawa J, Mogi T, Gennis RB, Anraku Y J. Biol Chem 267() 2096-2104 (1992)
H106G,L, H284G,L, H333L, H334L, H411G,L, H419G,L,N, H421G,L Cytochrome bo3 I E. coli Lemieux LJ, Calhoun MW, Thomas JW, Ingledew WJ, Gennis RB J. Biol Chem 267(), 2105-2113 (1992)
H548A, H333A, H419A Cytochrome bo3 I E. coli Uno T, Mogi T, Tsubaki M, Nishimura Y, Anraku Y J. Biol Chem 269(16), 11912-11920 (1994)
N172H, FG-Loop construction for introducing copper sites Cytochrome bo3 I and II E. coli van der Oost J, Lappalainen P, Musacchio A, Warne A, Lemieux L, Rumbley J, Gennis RB, Aasa R, Pascher T, Malmstrom BG, Saraste M EMBO J 11(), 3209-3217 (1992)
R2L/R4L, K5N/K8N, R4S/K5N/K8N, R2S/R4S/K5N/K8N, R2L/R4L/K5I/K8I, C25A, DR2S9 Cytochrome bo3 II E. coli Ma J, Katsonouri A, Gennis RB Biochemistry 36(38), 11298-11303 (1997)
E278Q,D, D124N,S, D399N Cytochrome aa3 I P. denitrificans Hellwig P, Behr J, Ostermeier C, Richter O-MH, Pfitzner U, Odenwald A, Ludwig B, Michel H, Mantele W Biochemistry 37(20):7390-7399 (1998)
D156N, D257N Cytochrome aa3 I P. denitrificans Witt H, Malatesta F, Nicoletti F, Brunori M, Ludwig B Eur J Biochem 251(1-2), 367-373 (1998)
Y35F, N113D,V, N113V/N131D, S134A, D124N,S, N131D,V, S189A, S193A, S189A/S193A, N199V, N199D/T203V, T203V, P277G, E278Q,D,N H325N, T344D,V, D399L,N, Y280H, S291A, H292L, K354M, W358F, E442Q, H448L, S456A, S489A/S490A, S496A Cytochrome aa3 I P. denitrificans Pfitzner U, Odenwald A, Ostermann T, Weingard L, Ludwig B, Richter O-M H J. Bioener Biomem 30(1), 89-97 (REVIEW)