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  • Shi Q, Chien YH, Leckband D. Biophysical properties of cadherin bonds do not predict cell sorting. J Biol Chem. 2008 Jun 15. Epub ahead of print.
  • Leckband D. Beyond structure: mechanism and dynamics of intercellular adhesion. Biochem Soc Trans. 2008 Apr;36(Pt 2):213-20.
  • Chien YH, Jiang N, Li F, Zhang F, Zhu C, Leckband D. Two stage cadherin kinetics require multiple extracellular domains but not the cytoplasmic region. J Biol Chem. 2008 Jan 25;283(4):1848-56.

  • Zhu, X., Yan, C., Winnik, F.M., Leckband, D.E. End-Grafted Low Molecular Weight PNIPAM Does Not Collapse above the LCST, Langmuir. 2007 23(1):162-9
  • Dong R, Jensen TW, Engberg K, Nuzzo RG, Leckband DE. Variably elastic hydrogel patterned via capillary action in microchannels. Langmuir. 2007 Jan 30;23(3):1483-8.
  • Bayas, M.V., Kearney, A., van der Merwe, P.A., Leckband, D.E. Impact of salt bridges on the equilibrium binding and adhesion of human CD2 and CD58,J Biol Chem. 2007 282(8):5589-96

  • Li, F., Leckband, D. (2006) Dynamic Strength of Molecularly Bonded Surfaces, J. Chem. Phys., 125, 194702.
  • Leckband, D., Prakasam, A. (2006) Mechanism and Dynamics of Cadherin Adhesion. Annu Rev Biomed Eng., 8, 259-287.
  • Prakasam, A., Maruthamuthu, V., Leckband, D.E. (2006) Similarities between Heterophilic and Homophilic Cadherin Adhesion, Proc Natl Acad Sci, 103, 15434-15439.
  • Wang, S.-C, Neoh, K.G., Kang, E.-T., Pack, D.W., Leckband, D.E. (2006) Heparinized Magnetic Nanoparticles: In-Vitro Assessment for Biomedical Applications, Adv. Functional Materials, 16, 1723-17.
  • Prakasam, A., Chien, Y.-H., Maruthamuthu, V., Leckband, D.E. (2006) Calcium site mutations in cadherin: impact on adhesion and evidence of cooperativity, Biochemistry, 49, 6930-6939.
  • Gunawan RC, Silvestre J, Gaskins HR, Kenis, P.J.A., Leckband, D.E. (2006) Cell migration and polarity on microfabricated gradients of extracellular matrix proteins, Langmuir, 22: 4250-4258.
  • Plunkett, KN, Zhu, X, Moore, JS, Leckband, D.E. (2006) PNIPAM chain collapse depends on the molecular weight and grafting density, Langmuir, 22: 4259-4266.
  • Bayas, M., Leung, A., Evans, E., Leckband, D. (2006) Lifetime Measurements Reveal Kinetic Differences between Homophilic Cadherin Bonds, Biophys. J., 90: 1385-1395.
  • Yan, C., Matsuda, W., Pepperberg, D.R., Zimmerman, S.C., Leckband, D.E. (2006) Synthesis and Characterization of an Electroactive Surface that Releases -Aminobutyric Acid (GABA), J. Coll. Int. Sci., 296: 165-177.

  • Hukkanen, E.J., Wieland, J.A., Gewirth, A.A., Braatz, R.D., Leckband, D.E. (2005) Multiple-bond Kinetics from Single-Molecules Pulling Experiments: Evidence for Multiple NCAM Bonds, Biophys. J., 89, 3434-3445.
  • Wieland, J.A., Gewirth, A., Leckband, D. (2005) Single Molecules Adhesion Measurements Reveal Two Homophilic NCAM Bonds with Mechanically Distinct Properties, J. Biol. Chem., 280: 41037-41046.
  • Wieland, J.A., Gewirth, A.A., Leckband, D.E., (2005) Single Molecule Measurements of the Impact of Lipid Phase Behavior on Anchor Strengths, J. Phys. Chem. B., 109, 5985-5993.
  • Gunawan, R.C., Choban, E.R., Conour, J.E., Schook, L.G., Gaskins, H.R., Kenis, P.J.A., Leckband, D.E. (2005) Regiospecific Control of Gene Expression in Cells Cultured on Two-component Counter Gradients of Extracellular Matrix Proteins, Langmuir, 21, 3061-3068.
  • Johnson, C.P., Fragnetto, G., Konovalov, O., Legrand, J.F., Leckband. D.E. (2005) Structural Studies of the Neural Cell Adhesion Molecule by X-Ray and Neutron Reflectivity, Biochemistry, 44, 546-554.
  • Johnson, C.P., Fujimoto, I., Rutishauser, U., Leckband, D.E. (2005) Direct Evidence that NCAM Polysialylation Increases Intermembrane Repulsion and Abrogates Adhesion, J. Biol. Chem., 280, 137-145.

  • Tan, W., Spendemir-Urkmez, Fahrner, L., Jamison, R., Leckband, D., Boppart, S.A. (2004) Structural and Functional Optical Imaging of Thee-Dimensional Engineered Tissue Development, Tissue Engineering, 10, 1747-1756.
  • Leckband, D. (2004) Adhesion Molecule NanoMechanics, Curr. Op. Struct. Biol., 14, 524-530.
  • Leckband, D. (2004) Novel Mechanisms of Cell Adhesion: new perspectives from force measurements, J. Adhesion, 80, 409-432.
  • Zhu, X., DeGraaf, J., Winnik, F.M., Leckband, D. (2004) pH Dependent Mucoadhesion of a Poly(N-isopropylacrylamide) Copolymer Reveals Design Rules for Drug Delivery, Langmuir, 20, 10648-10656.
  • Bayas, M., Schulten, K., Leckband, D. (2004) Forced Rupture of the Strand-dimer Interface between C-cadherin Ectodomains, Mechanics and Chemistry of Biosystems, 1:101-111.
  • Zhu, X., DeGraaf, J., Winnik, F., Leckband, D. (2004) pH-Responsive PNIPAM-N-Glycine Copolymer: Direct measurements of Interfacial Forces, Langmuir, 20, 1459-1465.
  • Johnson, C.P., Fujimoto, I., Perrin-Tricaud, C., Rutishauser, U., Leckband, D. (2004) Mechanism of Homophilic NCAM Adhesion: use of multiple domains and flexibility, Proc. Natl. Acad. Sci. USA, 101, 6963-6968.

  • Johnson, C., Prakasam, A., Jensen, I., Vijayendran, R., and Leckband, D. (2003) Engineered Protein A for the Orientational Control of Immobilized Proteins, Bioconjugate Chemistry, 14, 974-978.
  • Zhu, B., Chappuis-Flament, S., Wong, E., Jensen, I., Gumbiner, B.M., and Leckband, D.E. (2003) Functional Analysis of the Structural Basis of Homophilic Cadherin Adhesion, Biophys. J., 84, 4033-4042.
  • Bayas, M.V., Schulten, K.S., and Leckband, D. (2003) Forced dissociation of the CD2-CD58 Complex, ''Biophys. J.',84, 2223-2233.
  • Vijayendran, R, Motsegood, K.M., Beebe, D.J., Leckband, D.E. (2002) Evaluation of a Three-Dimensional Micromixer in a Surface-Based Biosensor, Langmuir, 19, 1824-1828.
  • Zhu, B., Davies, E.A., van der Merwe, A., Leckband, D. (2002) Direct Measurements of Heterotypic Adhesion Between the Cell Adhesion Proteins CD2 And CD48, Biochemistry, 42, 12163-12170.
  • Martel, L., Johnson, C., Boutet, S., Al- Kurdi, R., Konovalov, O., Robinson, I., Leckband, D., Legrand, J.F. (2002) X-Ray Reflectivity Investigation of the Structure of Cadherin Monolayers, J. Phys. IV France, 12, 365-377.
  • Efremova, NV, Huang, Y, Peppas, NA, and Leckband, D (2002) Direct Measurement of Interactions between Tethered PEG Chains and Adsorbed Mucin Layers, Langmuir, 18, 836-845

  • Efremova, NV, Sheth, S.R., and Leckband, D (2001) Protein-induced conformational changes in poly(ethylene glycol) brushes: molecular weight and temperature dependence, Langmuir, 17, 7628-7636.
  • Branch, DW, Wheeler, BC, Brewer, GJ, and Leckband, DE (2001) Long-Term Stability of Microstamped Substrates of Polylysine and Grafted Polyethylene Glycol in Cell Culture Conditions, "Biomaterials", 22:1035-1047.
  • Zhu, B., Eurell, T., Gunawan, R., Leckband, D. (2001) Protein adsorption and cell adhesion on oligo(ethylene glycol)-terminated self-assembled monolayers on gold, "J. Biomat. Sci. Polym. Ed.", 56, 406-416.
  • Sivasankar, S., Gumbiner, B., and Leckband, D. (2001) Molecular Mechanism of Cadherin Binding, "Biophys. J.", 80, 1758-1768.
  • Leckband, D. and Israelachvili, J.N. (2001) Forces in Biology, Quarterly Reviews of Biophysics, 34, 105-267.
  • Leckband, D. (2001) Novel Recognition Mechanisms in Biological Adhesion, Curr. Op. Coll. Sci., 6, 498-505.
  • Leckband, D. (2001) Force as a Probe of Membrane Structure and Function, Current Op. Struct. Biol., 11, 433-439.

  • Vijayendran, R. and Leckband, D. (2000) Quantitative Assessment of the Heterogeneity of Immobilized Antibodies, Anal. Chem., 73, 471-480.
  • Eteshola, E. and Leckband, D. (2000) Development of a Microfluidic ELISA Assay, Sensors and Actuators B, 72, 129-133.
  • Sheth, S.R., Efremova, N., and D. Leckband (2000) Interactions of Polyethylene Oxide Brushes with Chemically Selective Surfaces, J. Phys. Chem. B, 104, 7652-7662.
  • Efremova, N., Bondurant, B., O’Brien, D., and Leckband, D. (2000) Interaction Forces and Protein Resistance of Neutral Membranes with End-Grafted Poly(ethylene glycol), Biochemistry, 39, 3441-3451.
  • A. Kloss, N. Lavrik, C. Yeung, and D. Leckband (2000) Effect of the Microenvironment on the Apparent Affinity of Immobilized Receptors, Langmuir, 16, 3414-3421.
  • D. Branch, B. Wheeler, G. Brewer, and D. Leckband, Long-Term Maintenance of Patterns of Hippocampal Pyramidal Cells on Substrates of Polyethylene Glycol and Microstamped Polylysine (2000) IEEE Transactions on Biomedical Engineering, 47, 290-300.
  • N. Lavrik and D. Leckband (2000) Optical and Direct Force Measurements of Interactions Between Monolayers of Aromatic Macrocycles on Surfactant Membranes, Langmuir, 16, 1842-1851.
  • Halperin, A. and Leckband, D. (2000) From Ship Hulls to Contact Lenses: Repression of Protein Adsorption and the Puzzle of PEO, C.R. Acad. Sci., Paris, Serie IV, 1171-1178.
  • Leckband, D. and Sivasankar, S. (2000) Mechanisms of Cadherin Binding, Current Opinions in Cell Biology, 12, 587-592.
  • Leckband, D. (2000) Measuring Forces that Control Protein Interactions, Ann. Rev. Biophys. Biomol. Structure, 29, 1-26.
  • Leckband, D., T.Kuhl, H.K. Wang, W. Müller, J. Herron, and H. Ringsdorf (2000) Direct Force Measurements of Antibody-Antigen Interactions, Methods, 20, 329-340.
  • Leckband, D. and Sivasankar, S., Forces in Protein Interactions: Theory and Experiment, Colloids and Surfaces, B, Special DLVO Edition (2000) 14, 83-97.

  • Vijayendran, R., Ligler, F.S., and Leckband, D. (1999) A Computational Transport-Kinetic Model for the Analysis of Transport-Limited Biosensor Data, "Anal. Chem.", 71, 5455412.
  • S. Sivasankar, W. Brieher, N. Lavrik, B. Gumbiner, and D. Leckband, Direct Force Measurements of Multiple Adhesive Interactions Between Cadherin Ectodomains (1999) "Proc. Natl. Acad. Sci. USA", 96, 11820-4.
  • C. Yeung, T. Purves, A. Kloss, T. Kuhl, S. Sligar, and D. Leckband (1999), Cytochrome c Recognition of Immobilized Orientational Variants of Cytochrome b5: Direct Force and Equilibrium Binding Measurements "Langmuir", 15, 6829-6836.
  • Leckband, D., Sheth, S.R., and Halperin, A., (1999) Grafted Poly(ethylene oxide) Brushes as Nonfouling Surface Coatings, J. Biomat. Sci. Polym. Ed., 10, 1125-1147.

  • S. Sivasankar, S. Subramaniam, and D. Leckband (1998) Probing the Electrostatic Properties of Proteins at the Molecular Level, Proc. Natl. Acad. Sci., 95, 12961-12966.
  • T.L. Kuhl, J. Majewski, J.Y. Wong, S. Steinberg, D.E. Leckband, J.N. Israelachvili, and G.S. Smith (1998) The Structure of Polymer Decorated Biomembranes, Biophys. J., 75, 2352-2362.
  • D. E. Leckband, O.V. Borisov, and A. Halperin (1998) Cold and Hot Denaturation of Polysoaps, Macromolecules, 31, 2368-2374.
  • R. Vijayendran, D. Hammer, and D. Leckband (1998) Simulations of the adhesion between molecularly bonded surfaces in direct force measuremetns, J. Chem. Phys, 108, 7783-7794.
  • Z.-W. Yu, T. Calvert, and D. Leckband (1998) Forces Between Neutral Glycosphingolipids: Direct Evidence for Carbohydrate Attraction, "Biochemistry", 37, 1540-1550.
  • C. Yeung and D. Leckband, (1997) Molecular Level Characterization of Microenvironmental Influences on the Properties of Immobilized Proteins (1997) Langmuir, 13, 6746-6754.
  • T. Calvert and D. Leckband (1997) Two-Dimensional Protein Crystallization on Solid Supports, Langmuir, 13, 6737-6745.
  • S. Sheth and D. Leckband (1997) Direct Measurements of Attractive Interactions Between Proteins and Grafted Poly(ethylene oxide) Chains, Proc. Natl. Acad. Sci., 94, 8399-8404.
  • S. Sheth and D. Leckband (1997) Direct Measurements of Polymerization-Dependent Changes in Diacetylene Films, Langmuir, 13, 5652-5662.
  • Kuhl, T., Guo, Y., Alderfer, J., Berman, A., Leckband, D., Israelachvili, J., and Hui, S. (1996) Direct Measurement of Polyethylene Glycol Induced Depletion Attraction Between Lipid Bilayers, Langmuir, 12, 3003-3014.

  • Sasisekharan, R., Leckband, D., Godavarthi, R., Vankataraman, G., Cooney, C. and Langer, R. (1995) Heparinase I from Flavobacterium heparanum. The role of cysteine residue in catalysis as probed by chemical modification and site-directed mutagenesis, Biochemistry, 34, 14441-14448.
  • Balgi, G., Leckband, D.E., and Nitsche, J.M. (1995) Transport Effects on the Kinetics of Protein-Surface Binding, Biophys. J, 68, 2251-2260.
  • D. Leckband, T. Kuhl, H.-K. Wang, W. Müller, J. Herron, and H. Ringsdorf (1995) 4-4-20 anti-fluorescyl IgG Fab' Binding to Fluoresceinated Bilayers: The impact of protein and bilayer structure, Biochemistry, 34, 11467-11478.
  • D. Leckband, W. Müller, F.-J. Schmitt, and H. Ringsdorf (1995) Molecular Mechanisms Determining the Strength of Receptor-Mediated Intermembrane Adhesion, Biophys. J, 69, 1162-1169.
  • Leckband, D. (1995) Using the Soft Touch on Cell Surfaces, Biophys. J., 68, 2215-2216.
  • Leckband, D. (1995) The surface force apparatus-a tool for probing molecular protein interactions, Nature, 376, 617-618.
  • T.L. Kuhl, D.Leckband, and J.N. Israelachvili (1994) Modulation of interaction forces between lipid bilayers exposing short-chained ethylene oxide headgroups, Biophys. J, 66, 1479-1488.
  • D. Leckband, F.-J. Schmitt, W. Knoll, and J. Israelachvili (1994) Specific and Nonspecific Protein Interaction Forces: direct force measurements and observations of associated molecular rearrangements, Biochemistry, 33, 4611-4624.
  • Shivkumar, C., Israelachvili, J., Leckband, D., Schmitt, F.-J., Walker, S., and Zasadzinski, J. (1994) Higher order Self-Assembly of Vesicles via Site-Specific Binding, Science, 264, 1753-1756.
  • L. Evert, D. Leckband, and J. Israelachvili (1993) Structure and Dynamics of Ion Induced Domains in Free and Supported Monolayers and Bilayers, Langmuir, 10, 303-315.
  • Spinke, J., Liley, M., Schmitt, F-J., Guder, H.-J., Angermaier, L., Weisenhorn, A.L., Hansma, P.K., Helm, C.A., Leckband, D., Israelachvili, J., and Knoll, W. (1993) Supra-Biomolecular Architectures at Functionalized Surfaces, J. Chem. Phys., 99, 7012-7019.
  • D. Leckband, Y.-L. Chen, Israelachvili, J., H. Wickman, R. Zimmerman, and M. Fletcher (1993) Measurements of Conformational changes during Adhesion of Lipid and Protein (Polylysine and S-Layer) Surfaces, Biotech. Bioeng., 42, 167-177.
  • D. Leckband, C. Helm, J. Israelachvili (1993) The Role of Calcium in the Adhesion and Fusion of Mixed Lipid Bilayers, Biochemistry, 32, 1127-1140.
  • Leckband D. and Israelachvili, J. (1992) Determination of the Molecular Basis of Protein Function by Direct Force Measurements, Enzyme and Microbial Technology, Enzyme Microb. Technol, 15, 450-459.
  • D. Leckband, F.-J. Schmitt, W. Knoll, and J. Israelachvili (1992) Direct Measurement of a Long-Range Attraction and Molecular Rearrangements in Receptor-Ligand Interactions, Science, 255, 1419-142.
  • D. Leckband and R. Langer (1991) An Approach for the Stable Immobilization of Protein, Biotechnol. and Bioeng, 37, 227-237.
  • D. Leckband and G. Hammes (1988) Function of Tightly Bound Nucleotides on Membrane-Bound Chloroplast Coupling Factor, Biochemistry, 27, 3629-3633.
  • D. Leckband and G. Hammes (1987) Interactions Between Nucleotide Binding Sites on Chloroplast Coupling Factor One During ATP Hydrolysis, Biochemistry, 26, 2306-2312.
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