Recent Publications
Cell Adhesion and Molecular Mechanics
Johnson, C.P., Fujimoto, I., Perrin-Tricaud, C., Rutishauser, U., Leckband, D. (2004) Mechanism of Homophilic NCAM Adhesion: use of multiple domains and flexibility, Proc. Natl. Acad. Sci. USA, 101, 6963-6968. pdfZhu, B., Chappuis-Flament, S., Wong, E., Jensen,
Bayas, M.V., Schulten, K.S., and Leckband, D. (2003) Forced dissociation of the CD2-CD58 Complex, Biophys. J., 84, 2223-2233. pdf
Zhu, B., Davies, E.A., van der Merwe, A., Leckband, D. (2002) Direct Measurements of Heterotypic Adhesion Between the Cell Adhesion Proteins CD2 And CD48, Biochemistry, 42, 12163-12170. pdf
Sivasankar, S., Gumbiner, B., and Leckband, D. (2001) Direct Measurements
of Multiple Adhesive Alignments and Unbinding
Trajectories between Cadherin Extracellular Domains, Biophys. J.,
80, 1758-1768. pdf
S. Sivasankar, W. Brieher, N. Lavrik, B. Gumbiner, and D. Leckband, Direct Force Measurements of Multiple Adhesive Interactions Between Cadherin Ectodomains (1999) PNAS, 96, 11820-4. pdf
Biomaterials
Zhu, X., DeGraaf, J., Winnik, F., Leckband, D. (2004) Tuning the Interfacial
Properties of Grafted Chains with a
pH Switch, Langmuir, 20, 1459-1465. pdf
Efremova,
NV, Huang, Y, Peppas, NA, and Leckband, D (2002) Direct Measurement of Interactions
between Tethered PEG Chains and Adsorbed Mucin Layers, Langmuir,
18, 836-845 pdf
Zhu, B., Eurell, T., Gunawan, R., Leckband, D. (2001) Protein adsorption and cell adhesion on oligo(ethylene glycol)-terminated self-assembled monolayers on gold, J. Biomat. Sci. Polym. Ed., 56, 406-416. pdf
Efremova, N., Bondurant, B., O’Brien, D., and Leckband, D. (2000) Interaction Forces and Protein Resistance of Neutral Membranes with End-Grafted Poly(ethylene glycol), Biochemistry, 39, 3441-3451. pdf
BioSensors
Vijayendran, R, Motsegood, K.M., Beebe, D.J., Leckband, D.E. (2002) Evaluation of a Three-Dimensional Micromixer in a Surface-Based Biosensor, Langmuir, 19, 1824-1828. pdf
Vijayendran, R. and Leckband, D. (2000) Quantitative Assessment of the Heterogeneity of Immobilized Antibodies, Anal. Chem., 73, 471-480. pdf
Vijayendran, R., Ligler, F.S., and Leckband, D. (1999) A Computational Transport-Kinetic Model for the Analysis of Transport-Limited Biosensor Data, Anal. Chem., 71, 5455412. pdf
Reviews
Leckband, D. (2004) Adhesion Protein Nanomechanics, Curr. Op. Struct. Biol., 14, 524-530. pdf
Leckband, D. and Israelachvili, J.N. (2001) Intermolecular Forces in Biology,Quarterly Reviews of Biophysics, 34, 105-267. pdf
Leckband, D. (2000) Measuring Forces that Control Protein Interactions, Ann. Rev. Biophys. Biomol. Structure, 29, 1-26. pdf