The Luthey-Schulten Group


SeqQR 1.0.1

Sequence QR (SeqQR) is a program that generates a nonredundant set of proteins that represents the topology of the molecular phylogenetic tree of the homologous group.

SeqQR is available on the following platforms:

Representative papers related to SeqQR:

A. Sethi, P. O'Donoghue, and Z. Luthey-Schulten. Evolutionary profiles from the QR factorization of multiple sequence alignments. PNAS, 102:4045, 2005.

P. O'Donoghue and Z. Luthey-Schulten, Evolutionary profiles derived from the QR factorization of multiple structural alignments gives an economy of information. J. Mol. Biol., 346:875, 2005.

P. O'Donoghue, and Z. Luthey-Schulten. On the evolution of structure in aminoacyl-tRNA synthetases. Microbiol. Mol. Biol. Rev., 67:550, 2003.




MultiSeq 2.0

MultiSeq is an extension to VMD that provides a combined sequence and structure bioinformatics analysis environment. For more information, see the MultiSeq home page. VMD and MultiSeq are available for many platforms, including Windows, Mac OS X, Linux, and Solaris. They can be downloaded from the NIH Resource for Macromolecular Modeling and Bioinformatics. Tutorials are also available for learning how to use MultiSeq and VMD.

Representative papers related to MultiSeq:

E. Roberts, J. Eargle, D. Wright, and Z. Luthey-Schulten. MultiSeq: Unifying sequence and structure data for evolutionary analysis. BMC Bioinformatics, 7:382, 2006.

J. Eargle, D. Wright, and Z. Luthey-Schulten. Multiple Alignment of protein structures and sequences for VMD. Bioinformatics, 22:504, 2006

MultiSeq



Tessellator 1.0

Tessellator is an application for the tessellation of 3D volume in and around biological molecules. It creates Tcl script files which are run within VMD to visualize volumes in context with their associated molecular structures.

For help with installation and use of Tessellator, click here.

For supplementary material associated with the paper "Visualizing the Dual Space of Biological Molecules", click here.

Tessellator is available on the following platforms:

Representative paper related to Tessellator:

J Eargle, and Z. Luthey-Schulten, Visualizing the Dual Space of Biological Molecules. Comp. Biol. Chem., 30:219, 2006



School of Chemical Sciences